Background: Traditional risk factors do not explain all of the risk for incident coronary heart disease (CHD) events. Various new or emerging risk factors have the potential to improve global risk assessment for CHD. Purpose: To summarize the results ...
Background: C-reactive protein (CRP) may help to refine global risk assessment for coronary heart disease (CHD), particularly among persons who are at intermediate risk on the basis of traditional risk factors alone. Purpose: To assist the U.S. ...
Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings. To the Editor: The outcomes for living kidney donors, shown in the study by Ibrahim et al. (Jan. 29 issue),1 are ...
von Hippel-Lindau (VHL) disease is caused by germ-line mutations in the VHL tumor suppressor gene and is the most common cause of inherited renal cell carcinoma (RCC). Mutations in the VHL gene also occur in a large majority of sporadic cases of ...
Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings. To the Editor: In his Clinical Practice article on neurogenic orthostatic hypotension, Freeman (Feb. 7 issue)1 ...
-- cannot be found in the Handle System. Possible reasons for the error are: the DOI has not been created the DOI is cited incorrectly in your source the DOI does not resolve due to a system problem If you believe you have requested a DOI that should ...
Roy Freeman, M.B., Ch.B. This Journal feature begins with a case vignette highlighting a common clinical problem. Evidence supporting various strategies is then presented, followed by a review of formal guidelines, when they exist. The article ends with ...
Background The hyper-IgE syndrome (or Job's syndrome) is a rare disorder of immunity and connective tissue characterized by dermatitis, boils, cyst-forming pneumonias, elevated serum IgE levels, retained primary dentition, and bone abnormalities. ...
Akt kinases mediate cell growth and survival. Here, we report that a pro-apoptotic kinase, Mst1/STK4, is a physiological Akt1 interaction partner. Mst1 was identified as a component of an Akt1 multiprotein complex isolated from lipid raft-enriched ...
Background The hyper-IgE syndrome (or Job's syndrome) is a rare disorder of immunity and connective tissue characterized by dermatitis, boils, cyst-forming pneumonias, elevated serum IgE levels, retained primary dentition, and bone abnormalities. ...
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