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ORIGINAL ARTICLE: Iron-Overload-Related Disease in HFE Hereditary Hemochromatosis

Background Most persons who are homozygous for C282Y, the HFE allele most commonly asssociated with hereditary hemochromatosis, have elevated levels of serum ferritin and transferrin saturation. Diseases related to iron overload develop in some C282Y ...

From ALLEN, K. J., GURRIN, L. C., CONSTANTINE, C. C., OSBORNE, N. J., DELATYCKI, M. B., NICOLL, A. J., MCLAREN, C. E., BAHLO, M., NISSELLE, A. E., VULPE, C. D., ANDERSON, G. J., SOUTHEY, M. C., GILES, G. G., ENGLISH, D. R., HOPPER, J. L., OLYNYK, J. K., POWEL, New England Journal of Medicine -- Recent Issues,  16 Jan 2008

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